Myricetin alleviates ovalbumin-induced allergic rhinitis in mice by regulating Th1/Th2 balance

Autor:	Ya-Nan Shi, Jin-Zhu Su, Juan Wang, Jiang-Qiao Geng
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	allergic rhinitis gata3 interleukins myricetin montelukast ovalbumin th1/th2 balance Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5
Zdroj:	Asian Pacific Journal of Tropical Biomedicine, Vol 13, Iss 7, Pp 306-314 (2023)
Druh dokumentu:	article
ISSN:	2221-1691 2588-9222
DOI:	10.4103/2221-1691.380562
Popis:	Objective: To evaluate the effect of myricetin on ovalbumin (OVA)-induced allergic rhinitis in mice. Methods: Mice were sensitized and challenged using OVA (5%, 500 mL) intraperitoneally and intranasally, respectively, on an alternative day for 14 days, followed by administration of myricetin (50, 100, and 200 mg/kg) till day 21. Nasal symptoms, biochemical parameters, protein expressions, and histopathology were observed. Results: OVA-induced increased nasal symptoms including rubbing, sneezing, and discharge were significantly reduced by myricetin (100 and 200 mg/kg) (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/31777027a68749c0aec76d0c261603ba Zobrazit plný text záznamu View record in DOAJ