Chemical Composition and Antibacterial Effect of Plantago Major Extract on Periodontal Pathogens
| Autor: | Sandra Jessenia Pesantes-Sangay, Roger Damaso Calla-Poma, Margarita Fé Requena-Mendizabal, María Isabel Alvino-Vales, Pablo Alejandro Millones-Gómez |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada, Vol 20 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1519-0501 1983-4632 |
| Popis: | Objective: To determine the in vitro antibacterial effect of different concentrations of the ethanol extract of Plantago major (plantain) on Porphyromonas gingivalis and Fusobacterium nucleatum. Material and Methods: Bacterial susceptibility tests were used in conjunction with the agar diffusion test and the minimum inhibitory concentration (MIC) test using the broth macrodilution technique. Results: Different concentrations of ethanol extract (25%, 50%, 75% and 100%) dissolved in 70% ethanol were used, with a positive control (0.12% chlorhexidine + 0.05% cetyl-pyridinium chloride) and a negative control (70% alcohol). The extracts at 75% and 100% showed inhibition halos against both strains studied. With 0.12% chlorhexidine + 0.05% cetyl-pyridinium chloride, inhibition halos averaged 14.9 mm, in contrast to 70° alcohol, where no bacterial inhibition was observed. The MIC was 50% for both species. Conclusion: The ethanol extract of Plantago major presents an in vitro antibacterial effect on Porphyromonas gingivalis, they may have potential applications in food and pharmaceutical products. |
| Databáze: | Directory of Open Access Journals |
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