Adipose tissue stromal vascular fraction in the treatment of full thickness burns in rats

Autor: Alexandre Lamaro Cardoso, Maria Márcia Bachion, Júlia de Miranda Morais, Marcelo Silva Fantinati, Vera Lúcia Lima de Almeida, Ruy Souza Lino Júnior
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Acta Cirúrgica Brasileira, Vol 31, Iss 9, Pp 578-585 (2016)
Druh dokumentu: article
ISSN: 0102-8650
DOI: 10.1590/S0102-865020160090000002
Popis: ABSTRACT PURPOSE: To analyze the healing effects of stromal vascular fraction (SVF) application compared to wound dressing with 2% silver sulfadiazine in full thickness burn wounds in rats. METHODS: Animals were divided into two groups: 2% silver sulfadiazine group and SVF group. Both groups received occlusive bandages while the first one was treated with 2% silver sulfadiazine and the latter was treated with injections of SVF prepared from adipose tissue extracted from an animal donor. The animals were accompanied through 3, 7 and 30 days for evaluation of macroscopic, microscopic and morphometric aspects. RESULTS: On day three, a significant increase (p
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