Mannitol versus mannitol with hypertonic saline for brain relaxation during craniotomies using ultra-sonographic optic nerve sheath diameter
| Autor: | Eslam Mohammed Ahmed El-Genaidy, Said Mohamed El-Medany, Ashraf Arafat Abdelhalim, Ragab Saad Beltagy, Tarek Ahmed Rayan |
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| Jazyk: | angličtina |
| Rok vydání: | 2025 |
| Předmět: | |
| Zdroj: | Alexandria Journal of Medicine, Vol 61, Iss 1, Pp 88-95 (2025) |
| Druh dokumentu: | article |
| ISSN: | 20905068 2090-5076 2090-5068 |
| DOI: | 10.1080/20905068.2024.2431755 |
| Popis: | Background This study compared the effect of conventional doses of mannitol alone versus combined lower doses of mannitol-hypertonic saline on brain debulking during elective craniotomies.Patients and methods Sixty participants aged 18–60 years, ASA class I or II, who were scheduled for elective supratentorial brain tumor surgery, were randomly separated into 2 equal groups. Group (M) received 5 ml/kg of 20% mannitol at the onset of the surgical incision over 15 min. Group (MH) received 2.5 ml/kg of 20% mannitol plus 2.5 ml/kg 3% hypertonic saline (HTS) at the onset of the surgical incision over 15 min. Optic nerve sheath diameter (ONSD), brain relaxation score, serum lactate, electrolytes, and surgeon’s satisfaction were measured.Results Both groups yielded similar results concerning demographic and tumor characteristics. The Optic nerve sheath diameter (ONSD) was considerably lower in group MH compared to group M just before and immediately after dural incision (p = |
| Databáze: | Directory of Open Access Journals |
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