Utility of Neutrophil–lymphocyte Ratio and Platelet–lymphocyte Ratio in Predicting Malignancy in Patients with Small Renal Mass
| Autor: | KR Surag, Anupam Choudhary, Anshuman Singh, PM Swathi, Kasi Vishwanath, Goli Abhishek, Mithun Rao |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Medical Journal of Dr. D.Y. Patil Vidyapeeth, Vol 17, Iss Suppl 2, Pp S333-S338 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2589-8302 2589-8310 |
| DOI: | 10.4103/mjdrdypu.mjdrdypu_872_23 |
| Popis: | Background: Abdominal imaging has become increasingly prevalent, resulting in the incidental detection of renal tumors. The majority of small renal masses (SRMs), which are surgically removed, prove to be malignant. However, some cases turn out to be benign, which can lead to unnecessary surgeries with associated significant morbidity. Recently, many inflammatory biomarkers have shown to be promising prognostic factors in RCC. We aimed to assess the importance of inflammatory biomarkers, which are simple and economical, in SRMs. Objective: We investigated whether preoperative neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) can predict malignancy in patients with SRMs. Material and Methods: A retrospective analysis was performed on 108 patients who underwent partial or radical nephrectomy for SRMs (tumors smaller than 4 cm) from January 2016 to December 2022. The patients were classified into two groups based on their histopathological diagnosis: benign group (n = 28) and malignant group (n = 80). NLR and PLR values were assessed for sensitivity using the ROC curve. Independent t-test, Mann–Whitney test, and Chi-square test were utilized. P |
| Databáze: | Directory of Open Access Journals |
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