Les mécanismes de repliement des protéines solubles

Autor:	Brasseur B., Benhabilès N., Thomas A.
Jazyk:	English<br />French
Rok vydání:	2000
Předmět:	Protein folding primary structure secondary structure tertiary structure hydrophobicity structure-function Biotechnology TP248.13-248.65 Environmental sciences GE1-350
Zdroj:	Biotechnologie, Agronomie, Société et Environnement, Vol 4, Iss 2, Pp 71-81 (2000)
Druh dokumentu:	article
ISSN:	1370-6233 1780-4507
Popis:	Mechanisms of folding of soluble proteins. The function of a protein is carried out by its three-dimensional structure. The rules for translation of the information encoded by DNAinto an amino acid sequence are well known. On the other hand, the rules governing the folding of an amino acid sequence into an univocal three-dimensional structure are still unknown. The speed at which this phenomenon takes place makes the experimental investigations difficult using biophysical methods. Various theoretical approaches have been set up with more or less success. None, nowadays, describes in a right way, the mechanisms involved. We present here the various hypotheses found in the literature about the early steps of the folding of soluble proteins.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/313583b38cab4b7f8cba694bc2abd3c8 Zobrazit plný text záznamu View record in DOAJ