A Review of Newly Diagnosed Glioblastoma

Autor: Bryan Oronsky, Tony R. Reid, Arnold Oronsky, Navjot Sandhu, Susan J. Knox
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Oncology, Vol 10 (2021)
Druh dokumentu: article
ISSN: 2234-943X
DOI: 10.3389/fonc.2020.574012
Popis: Glioblastoma is an aggressive and inevitably recurrent primary intra-axial brain tumor with a dismal prognosis. The current mainstay of treatment involves maximally safe surgical resection followed by radiotherapy over a 6-week period with concomitant temozolomide chemotherapy followed by temozolomide maintenance. This review provides a summary of the epidemiological, clinical, histologic and genetic characteristics of newly diagnosed disease as well as the current standard of care and potential future therapeutic prospects.
Databáze: Directory of Open Access Journals