| Autor: |
Gagandeep Kaur, Raju Padiya, Ramu Adela, Uday Kumar Putcha, Sweeya Reddy, Raghunath Reddy, Praveen Kumar, Sumana Chakravarty, Sanjay Kumar Banerjee |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Frontiers in Pharmacology, Vol 7 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
1663-9812 |
| DOI: |
10.3389/fphar.2016.00360 |
| Popis: |
Abstract:The study was aimed at finding the effect of garlic and resveratrol on loss of β-cells and diabetic complication in streptozotocin (STZ)-induced Type-I diabetic rats. Rats were injected with single dose STZ (50mg/kg, i.p.) for induction of type 1 diabetes (Dia) and compared with control group. Rats from third (Dia+Gar), fourth (Dia+Resv) and fifth (Dia+Met) groups were fed raw garlic homogenate (250 mg/kg/day), resveratrol (25 mg/kg/day) and metformin (500 mg/kg/day) orally, respectively for a period of 4 weeks. Diabetic group had decreased serum insulin and hydrogen sulfide levels along with increased blood glucose and glycated hemoglobin, triglyceride, uric acid and nitric oxide levels. Significant (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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