Sarcopenia in chronic liver disease, can we predict complications?
| Autor: | U. R. Salimov, I. O. Stoma, D. A. Fedoruk, A. A. Kovalev, A. E. Scherba, O. O. Rummo |
|---|---|
| Jazyk: | English<br />Russian |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Трансплантология (Москва), Vol 14, Iss 4, Pp 408-420 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2074-0506 2542-0909 |
| DOI: | 10.23873/2074-0506-2022-14-4-408-420 |
| Popis: | Introduction. Sarcopenia is a common complication of chronic liver disease. Today many studies are devoted to sarcopenia impact on the course of liver diseases. At the same time, many studies are being performed on the correlation of sarcopenia in patients with cirrhosis of the liver and the incidence of early complications after liver transplantation. In this regard, we conducted our own retrospective study of the correlation relationship of sarcopenia in patients with chronic liver diseases.Aim. To determine the correlation between the severity of sarcopenia and the incidence of complications of liver cirrhosis in patients on the waiting list for liver transplantation.Material and methods. In our own retrospective observational study, 87 patients suffering from chronic liver diseases and treated at the Minsk Scientific and Practical Center of Surgery, Transplantation and Hematology were included. The assessment of sarcopenia was carried out using the CT technique for assessing indexed parameters of the patient's muscle mass. Mathematical processing was performed using the FDA-approved OsirixTM software. The study was conducted within the framework of the project "ClinicalTrials: NCT04281797"Results. Body mass index was significantly correlated with the presence of sarcopenia (rpb=-0.48, 95% CI [-0.65;-0.27]). At the same time, the groups of patients with and without sarcopenia differed significantly (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|