Efficacy of prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review meta-analysis

Autor: Yang Xu, Shuai Shao, ZeZhong Gong, HyokJu Ri, ZhaoHui Xu, HaoNan Kang, Yan Shan, Boureima Hamidou Amadou, YanYing Ren, Fan Zhang, Xin Chen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Surgery, Vol 23, Iss 1, Pp 1-12 (2023)
Druh dokumentu: article
ISSN: 1471-2482
DOI: 10.1186/s12893-023-02280-4
Popis: Abstract Introduction The susceptibility to surgical site occurrence (SSO) is high following ventral hernia repair (VHR) surgery. SSO severely increases the physical and mental burden on patients. The main purpose of this review was to analyze the efficacy of negative pressure wound therapy (NPWT) after open VHR(OVHR) and explore benefits to patients. Methods The Cochrane Library, PubMed, and Embase databases were searched from the date of establishment to 15 October 2022. All randomized controlled trials and retrospective cohort studies comparing NPWT with standard dressings after OVHR were included. The Revman 5.4 software recommended by Cochrane and the STATA16 software were used in this meta-analysis. Results Fifteen studies (involving 1666 patients) were identified and included in the meta-analysis, with 821 patients receiving NPWT. Overall, the incidence rate of SSO in the NPWT group was lower compared to the control group (odds ratio [OR] = 0.44; 95% confidence interval [CI] = 0.21–0.93; I2 = 86%; P = 0.03). The occurrence rate of surgical site infection (SSI; OR = 0.51; 95% CI = 0.38–0.68, P
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