| Autor: |
Stephan Skornitzke, Neha Vats, Taisiya Kopytova, Elizabeth Wai Yee Tong, Tobias Hofbauer, Tim Frederik Weber, Christoph Rehnitz, Oyunbileg von Stackelberg, Klaus Maier-Hein, Wolfram Stiller, Jürgen Biederer, Hans-Ulrich Kauczor, Claus-Peter Heußel, Mark Wielpütz, Viktoria Palm |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-022-24546-2 |
| Popis: |
Abstract Asynchronous calibration could allow opportunistic screening based on routine CT for early osteoporosis detection. In this phantom study, a bone mineral density (BMD) calibration phantom and multi-energy CT (MECT) phantom were imaged on eight different CT scanners with multiple tube voltages (80–150 kVp) and image reconstruction settings (e.g. soft/hard kernel). Reference values for asynchronous BMD estimation were calculated from the BMD-phantom and validated with six calcium composite inserts of the MECT-phantom with known ground truth. Relative errors/changes in estimated BMD were calculated and investigated for influence of tube voltage, CT scanner and reconstruction setting. Reference values for 282 acquisitions were determined, resulting in an average relative error between calculated BMD and ground truth of − 9.2% ± 14.0% with a strong correlation (R 2 = 0.99; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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