| Autor: |
Andrea Ivonne Loewendorf, Marie eCsete, Alan eFlake |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Frontiers in Pharmacology, Vol 5 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1663-9812 |
| DOI: |
10.3389/fphar.2014.00282 |
| Popis: |
In utero hematopoetic Stem cell transplantation (IUHCT) is an attractive approach and a potentially curative surgery for several congenical hematopoetic diseases. In practice, this application has succeeded only in the context of Severe Combined Immunodeficiency Disorders. Here, we review potential immunological hurdles for the long-term establishment of chimerism and discuss relevant models and findings from both postnatal hematopoetic stem cell transplantation and IUHCT. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
