Gonococcal urethritis caused by a multidrug resistant Neisseria gonorrhoeae strain with high-level resistance to spectinomycin in China

Autor:	Shao-Chun Chen, Li-Hua Hu, Xiao-Yu Zhu, Yue-Ping Yin
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Neisseria gonorrhoeae spectinomycin resistance urethritis treatment failure Infectious and parasitic diseases RC109-216 Microbiology QR1-502
Zdroj:	Emerging Microbes and Infections, Vol 9, Iss 1, Pp 517-519 (2020)
Druh dokumentu:	article
ISSN:	22221751 2222-1751
DOI:	10.1080/22221751.2020.1732836
Popis:	ABSTRACTWe report a recent (2018) gonorrhoeal urethritis caused by a multidrug-resistant Neisseria gonorrhoeae strain in China. The isolated N. gonorrhoeae strain from a male and female pair expressed high-level resistance to spectinomycin (SPC), azithromycin, and other antibiotics but was sensitive to ceftriaxone. The SPC high-level resistance (MIC = 2048 mg/L) was due to a small deletion in rspE that caused two amino acid changes in ribosomal protein S5.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/30cc172b92fa46e9bf62ca78ee2e938f Zobrazit plný text záznamu View record in DOAJ