Video‐assisted thoracoscopic surgery versus open thoracotomy for resection of lung metastasis—A meta‐analysis of reconstructed time‐to‐event data

Autor: Felipe S. Passos, Pedro B. Bregion, Luca Fazzini, Hristo Kirov, Tim Sandhaus, Patrick vonSamson, Torsten Doenst, Tulio Caldonazo
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Thoracic Cancer, Vol 15, Iss 34, Pp 2401-2407 (2024)
Druh dokumentu: article
ISSN: 1759-7714
1759-7706
DOI: 10.1111/1759-7714.15473
Popis: Abstract This study aimed to conduct a systematic review and meta‐analysis comparing video‐assisted thoracoscopic surgery (VATS) and open thoracotomy (OT) in the context of pulmonary metastasectomy. Three databases were assessed. The primary outcome was overall survival. The secondary outcomes were recurrence‐free survival, ipsilateral recurrence, and hospital length of stay (LOS). Hazard ratios (HRs), odds ratios (ORs), and mean difference (MD) with 95% confidence intervals (CIs) were calculated. Reconstruction of time‐to‐event data and sensitivity analyses were performed for the primary endpoint. After screening, 11 studies were included encompassing 2159 patients undergoing lung metastasectomy (VATS: 827; OT: 1332). Compared to OT, patients who underwent VATS had higher overall survival rates (HR 0.75; 95% CI 0.67–0.85; p
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje