Mortality, severe acute respiratory infection, and influenza-like illness associated with influenza A(H1N1)pdm09 in Argentina, 2009.

Autor: Eduardo Azziz-Baumgartner, Ana María Cabrera, Loretta Chang, Rogelio Calli, Gabriela Kusznierz, Clarisa Baez, Pablo Yedlin, Ana María Zamora, Romina Cuezzo, Elena Beatriz Sarrouf, Andrea Uboldi, Juan Herrmann, Elsa Zerbini, Osvaldo Uez, Pedro Osvaldo Rico Cordeiro, Pollyanna Chavez, George Han, Julián Antman, Fatima Coronado, Joseph Bresee, Marina Kosacoff, Marc-Alain Widdowson, Horacio Echenique
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: PLoS ONE, Vol 7, Iss 10, p e47540 (2012)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0047540
Popis: INTRODUCTION: While there is much information about the burden of influenza A(H1N1)pdm09 in North America, little data exist on its burden in South America. METHODS: During April to December 2009, we actively searched for persons with severe acute respiratory infection and influenza-like illness (ILI) in three sentinel cities. A proportion of case-patients provided swabs for influenza testing. We estimated the number of case-patients that would have tested positive for influenza by multiplying the number of untested case-patients by the proportion who tested positive. We estimated rates by dividing the estimated number of case-patients by the census population after adjusting for the proportion of case-patients with missing illness onset information and ILI case-patients who visited physicians multiple times for one illness event. RESULTS: We estimated that the influenza A(H1N1)pdm09 mortality rate per 100,000 person-years (py) ranged from 1.5 among persons aged 5-44 years to 5.6 among persons aged ≥ 65 years. A(H1N1)pdm09 hospitalization rates per 100,000 py ranged between 26.9 among children aged
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