Human pluripotent stem cells in contemporary medicine
| Autor: | S. A. Rodin |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Issledovaniâ i Praktika v Medicine, Vol 2, Iss 2, Pp 44-52 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2410-1893 2409-2231 |
| DOI: | 10.17709/2409-2231-2015-2-2-44-52 |
| Popis: | Human pluripotent stem cells (hPSCs) are capable of indefinite proliferation and can be differentiated into any cell type of the human body. Therefore, they are a promising source of cells for treatment of numerous degenerative diseases and injuries. Pluripotent stem cells are also associated with a number of ethical, safety and technological issues. In this review, we describe various types of hPSCs, safety issues that concern all or some types of hPSCs and methods of clinical-grade hPSC line development. Also, we discuss current and past clinical trials involving hPSCs, their outcomes and future perspectives of hPSC-based therapy. |
| Databáze: | Directory of Open Access Journals |
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