HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data

Autor: Lydia Mok, Taesung Park
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Genomics & Informatics, Vol 17, Iss 4 (2019)
Druh dokumentu: article
ISSN: 2234-0742
DOI: 10.5808/GI.2019.17.4.e45
Popis: To identify pathways associated with survival phenotypes using gene expression data, we recently proposed the hierarchical structural component model for pathway analysis of gene expression data (HisCoM-PAGE) method. The HisCoM-PAGE software can consider hierarchical structural relationships between genes and pathways and analyze multiple pathways simultaneously. It can be applied to various types of gene expression data, such as microarray data or RNA sequencing data. We expect that the HisCoM-PAGE software will make our method more easily accessible to researchers who want to perform pathway analysis for survival times.
Databáze: Directory of Open Access Journals