| Autor: |
Diego Odetto, Guido Martin Rey Valzacchi, Marcela Ostojich, Sebastian Alessandria, Maria Cecilia Darin, Karen Tapper, Alicia Rita Amato, Federico Luis Bianchi, Eduardo Fabian Lopresti, Lorena Soledad Cabrera, Jerónimo Costa, Agustín Esteban, Luciana Prozzillo, Horacio Escobar, Daniel Gacitua Bustos, Otilio Daniel Rosato, Ricardo Anibal Picciochi, Rosa María Garrido, Graciela Lopez de Degani, María Soledad Del Valle Vitale, Roberto Hugo Navarini, Facundo Isnardi, Gonzalo Franco, Mariano Rossini, María Mercedes Carrizo, Myriam Perrotta, Gabriel Crimi |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Gynecologic Oncology Reports, Vol 46, Iss , Pp 101147- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2352-5789 |
| DOI: |
10.1016/j.gore.2023.101147 |
| Popis: |
Objective: Compare the perioperative outcomes and disease-free survival between minimally invasive and open surgery in women with stage I–II high-risk endometrial cancer. Methods: A retrospective, cohort study was performed involving twenty-four centers from Argentina. Patients with grade 3 endometrioid, serous, clear cell, undifferentiated carcinoma or carcinosarcoma who underwent hysterectomy, bilateral salpingo-oophorectomy, and staging between January 2010–2018 were included. Cox hazard regression analysis and Kaplan-Meier curves evaluated the association of surgical technique with survival. Results: Of 343 eligible patients, 214 (62 %) underwent open surgery and 129 (38 %) underwent laparoscopic surgery. No significant differences were seen between the two groups with respect to greater or equal grade III Clavien-Dindo postoperative complications (11 % in the open surgery group vs 9 % minimally invasive surgery group; P = 0.34) Minimally invasive surgery was not associated with worse disease-free survival at four years (79.14 % [95 % CI 69.42– 86.08] vs 78.80 % [95 % CI 70.61–84.96]), (p = 0.25), even after creating a Cox proportional model (hazard ratio [HR] 1.08 95 % CI 0.63–1.84); (p = 0.76). Conclusion: There was no difference between postoperative complications nor oncologic outcomes comparing minimally invasive and open surgery among patients with high-risk endometrial cancer. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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