Association between Hasford Scoring System and Hematologic Response in Chronic and Accelerated Phase of Chronic Myelocytic Leukemia Patient with Imatinib for Three Months
| Autor: | Andy Purnomo, Ugroseno Yudho Bintoro, Made Putra Sedana, Ami Ashariati |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | MCBS (Molecular and Cellular Biomedical Sciences), Vol 3, Iss 2, Pp 88-94 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2527-4384 2527-3442 |
| DOI: | 10.21705/mcbs.v3i2.56 |
| Popis: | Background: Hasford score is a scoring system which was made in interferon treatment era to assess chronic myelocytic leukemia (CML) prognosis. Complete hematologic response (CHR) is the milestone of prognosis evaluation. CHR achievement will significantly increase survival. Imatinib is a revolutionized treatment that change the prognosis of CML. With the advent of Imatinib, lessened the prognostic impact of the Hasford score to predict prognosis. Materials and Methods: An observational analytic with prospective cohort study conducted in oncology outward division Dr. Soetomo hospital Surabaya, from July until October 2018. Hasford score determined in 32 patients at the beginning of the study, given imatinib and followed up regularly for 3 months to know the hematologic response. Data were analyzed using Fisher exact test which was considered significant if p |
| Databáze: | Directory of Open Access Journals |
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