Functionalized Antimicrobial Nanofibers: Design Criteria and Recent Advances

Autor: Nazirah Hamdan, Alisa Yamin, Shafida Abd Hamid, Wan Khartini Wan Abdul Khodir, Vincenzo Guarino
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Functional Biomaterials, Vol 12, Iss 4, p 59 (2021)
Druh dokumentu: article
ISSN: 2079-4983
DOI: 10.3390/jfb12040059
Popis: The rise of antibiotic resistance has become a major threat to human health and it is spreading globally. It can cause common infectious diseases to be difficult to treat and leads to higher medical costs and increased mortality. Hence, multifunctional polymeric nanofibers with distinctive structures and unique physiochemical properties have emerged as a neo-tool to target biofilm and overcome deadly bacterial infections. This review emphasizes electrospun nanofibers’ design criteria and properties that can be utilized to enhance their therapeutic activity for antimicrobial therapy. Also, we present recent progress in designing the surface functionalization of antimicrobial nanofibers with non-antibiotic agents for effective antibacterial therapy. Lastly, we discuss the future trends and remaining challenges for polymeric nanofibers.
Databáze: Directory of Open Access Journals