The glucose infusion rate of parenteral nutrition in the first week of life in preterm infants: an observational study

Autor: Dina Angelika, Risa Etika, Martono Tri Utomo, Setya Mirha, Kartika Darma Handayani, I. Dewa Gede Ugrasena
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Italian Journal of Pediatrics, Vol 47, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1824-7288
DOI: 10.1186/s13052-021-01165-7
Popis: Abstract Background Most preterm infants require a continuous glucose infusion in the early postnatal period due to the interruption of the transplacental glucose supply after birth to promote better neurodevelopmental outcomes. Aims To investigate the glucose infusion rate (GIR) on parenteral nutrition (PN) in the first week of life administered in preterm infants and its effect on neonatal morbidity and mortality. Methods This study included 97 infants aged 13–15 g/kg/day (Group III). Univariate and multivariate logistic regression analyzes were carried out to investigate whether the GIR usage in the three groups was associated with selected neonatal morbidities and mortality. Neonatal morbidities analyzed included respiratory distress syndrome (RDS), necrotizing enterocolitis, sepsis, retinopathy of prematurity, pulmonary hypertension, hypoglycemia, and hyperglycemia. Result Of 97 preterm infants included, 51.5% infants had a gestational age of 34-
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