Assessment of Compound Pueraria lobate and Ophiopogon japonicus Tea on Hypoglycaemic Activity

Autor: Xin LI, Mei CHEN, Yi XI, Xin WANG, Yuanyuan SHAN, Xin LÜ
Jazyk: čínština
Rok vydání: 2022
Předmět:
Zdroj: Shipin gongye ke-ji, Vol 43, Iss 12, Pp 347-353 (2022)
Druh dokumentu: article
ISSN: 1002-0306
DOI: 10.13386/j.issn1002-0306.2021100113
Popis: This study aimed to explore the hypoglycaemic effects of the compound Pueraria lobate and Ophiopogon japonicus tea. In this study, the compound Pueraria lobate and Ophiopogon japonicus tea was administered to normal mice. Moreover, a mouse model of hyperglycemia was established, and high (3.0 g/kg BW), medium (2.0 g/kg BW), and low (1.0 g/kg BW) doses of compound Pueraria lobate and Ophiopogon japonicus tea were administered to mice with hyperglycemia. The body weight, blood glucose and glucose tolerance indexes of the mice were detected. In addition, the control group was given placebo and the experimental group was given compound Pueraria lobate and Ophiopogon japonicus tea twice a day, 3 g each time for 60 days in hyperglycemic people. The changes in glycosylated hemoglobin, blood glucose and clinical symptoms were observed. The results showed that compound Pueraria lobate and Ophiopogon japonicus tea had no effect on the body weight and blood glucose in normal mice, but the 2 h blood glucose of hyperglycemic model mice in high and medium dose groups were decreased significantly and extremely significantly, respectively (P
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