| Autor: |
Kristofer Wollein Waldetoft, Lars Råberg, Rolf Lood |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Evolutionary Applications, Vol 13, Iss 5, Pp 879-888 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1752-4571 |
| DOI: |
10.1111/eva.12952 |
| Popis: |
Abstract Key topics in the study of host–microbe interactions—such as the prevention of drug resistance and the exploitation of beneficial effects of bacteria—would benefit from concerted efforts with both mechanistic and evolutionary approaches. But due to differences in intellectual traditions, insights gained in one field rarely benefit the other. Here, we develop a conceptual and analytical framework for the integrated study of host–microbe interactions. This framework partitions the health effects of microbes and the effector molecules they produce into components with different evolutionary implications. It thereby facilitates the prediction of evolutionary responses to inhibition and exploitation of specific molecular mechanisms. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Plný text