A Rare Case of Metachronous Peripheral T-cell Non-Hodgkin Lymphoma Following Epstein-barr Virus-positive Diffuse Large B-cell Lymphoma, Not Otherwise Specified

Autor: Latha Abraham, Mobin Paul, Sophy M. P., Dasary Varghese, Chryselle Olive D’Souza
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Oman Medical Journal, Vol 38, Iss 2, Pp e487-e487 (2023)
Druh dokumentu: article
ISSN: 1999-768X
2070-5204
DOI: 10.5001/omj.2023.13
Popis: We report a case of an elderly male who presented with enlarged abdominal lymph nodes and was diagnosed as having Epstein-Barr virus-positive diffuse large B-cell lymphoma, not otherwise specified (EBV+ DLBCL, NOS). He was started on chemotherapy which had to be discontinued after three cycles due to the development of life-threatening pneumocystis carinii pneumonia and poor performance status. Within two years, the patient presented with features of relapse. A repeat histopathological examination of the lymph node showed features of peripheral T-cell lymphoma, NOS and the clonality was confirmed by T-cell receptor gamma chain rearrangement assay. More studies are needed to understand the association of EBV+ DLBCL, NOS with other lymphomas.
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