Metagenomic Approaches as a Tool to Unravel Promising Biocatalysts from Natural Resources: Soil and Water

Autor: Joana Sousa, Sara C. Silvério, Angela M. A. Costa, Ligia R. Rodrigues
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Catalysts, Vol 12, Iss 4, p 385 (2022)
Druh dokumentu: article
ISSN: 2073-4344
DOI: 10.3390/catal12040385
Popis: Natural resources are considered a promising source of microorganisms responsible for producing biocatalysts with great relevance in several industrial areas. However, a significant fraction of the environmental microorganisms remains unknown or unexploited due to the limitations associated with their cultivation in the laboratory through classical techniques. Metagenomics has emerged as an innovative and strategic approach to explore these unculturable microorganisms through the analysis of DNA extracted from environmental samples. In this review, a detailed discussion is presented on the application of metagenomics to unravel the biotechnological potential of natural resources for the discovery of promising biocatalysts. An extensive bibliographic survey was carried out between 2010 and 2021, covering diverse metagenomic studies using soil and/or water samples from different types and locations. The review comprises, for the first time, an overview of the worldwide metagenomic studies performed in soil and water and provides a complete and global vision of the enzyme diversity associated with each specific environment.
Databáze: Directory of Open Access Journals
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