| Autor: |
Anastase Dzudie, Messaline Fodom Fomo, Denis Georges Teuwafeu, Clovis Nkoke, Azabji Kenfack, Divine Tim Bonghaseh, Domin Ekaney, Amy Tantchou, Cabral Tantchou, Laurent Serges Etoundi Ngoa, Andre Pascal Kengne, Simeon Pierre Choukem |
| Jazyk: |
English<br />French |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
The Pan African Medical Journal, Vol 37, Iss 122 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1937-8688 |
| DOI: |
10.11604/pamj.2020.37.122.21156 |
| Popis: |
INTRODUCTION: Several international guidelines are available on drug treatment for hypertension, but the control of hypertension remains very poor in sub-Saharan Africa (SSA). We investigated the commonly prescribed antihypertensive drugs and their association with blood pressure (BP) control in adult Cameroonians. METHODS: we consecutively recruited hypertensive outpatients attending the Buea and Limbe Regional Hospitals (Southwest Region of Cameroon). Controlled BP was defined as BP 140/90mmHg in hypertensive patients aged 60 years or younger, diabetics or patients with chronic kidney disease or a BP 150/90mmHg in non-diabetic hypertensive patients older than 60 years of age (JNC8). RESULTS: of the 408 participants included (mean age 61.1 years), 67% were female. The median duration of hypertension was 6 years and the median duration of the current treatment was 22 weeks. Commonly prescribed antihypertensives were calcium channel blockers (CCB, 35.1%), thiazide/thiazide-like diuretics (TD/TLD, 26.1%) and angiotensin-converting enzyme inhibitors (ACEI,19.5%). The median monthly cost of antihypertensive was 10279.6 CFA (approximately equal to US$ 172). 70% of participants were receiving at least 2 drugs, with ACEI+TD/TLD, CCB+TD/TLD, and ACEI+CCB+TD/TLD being the most frequent. The rate of BP control was 52% overall, and 60% in participants on monotherapy. CONCLUSION: CCBs were the most prescribed single antihypertensive drugs in this setting while ACEI+TD/TLD was the most common combination. About half of patients were at target BP control levels Improving availability and affordability of these medications may improve hypertension management and control. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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