Rosai-Dorfman Disease Presenting as Recurrent Nasal Polyposis
| Autor: | Neil Louis L. Apale, Joel A. Romualdez, Rodolfo E. Rivera |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Philippine Journal of Otolaryngology Head and Neck Surgery, Vol 29, Iss 2 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1908-4889 2094-1501 |
| DOI: | 10.32412/pjohns.v29i2.419 |
| Popis: | Objective: To present a case of Rosai-Dorfman disease in an individual with a 14-year history of recurrent nasal polyposis, and discuss its clinical presentation, physical examination, radiologic findings, histopathologic characteristics, and available treatment. Methods: Design: Case Report Setting: Tertiary Private Hospital Patient: One Result: A 26-year-old Filipino diagnosed and repeatedly treated medically and surgically for recurrent nasal polyposis underwent repeat endoscopic sinus surgery. A histopathologic impression of Rosai-Dorfman disease was confirmed by positive S-100 and CD1a negative immunochemistry in conjunction with the morphologic findings. Conclusion: Rosai-Dorfman disease is a rare entity which should be considered when dealing with recurrent nasal polyposis that is intractable to initial medical and surgical therapies. Histopathologic findings of emperipolesis and immunohistochemical S-100 stains play a key role in the diagnosis, but there is yet no definite treatment for this disease. Keywords: recurrent nasal polyposis, Rosai-Dorfman disease, emperipolesis, S-100 stain |
| Databáze: | Directory of Open Access Journals |
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