Advances in Predictive Research of Immune Checkpoint Inhibitors-related Adverse Events

Autor: Jing ZHANG, Xueqin CHEN, Shenglin MA
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Chinese Journal of Lung Cancer, Vol 26, Iss 10, Pp 789-794 (2023)
Druh dokumentu: article
ISSN: 1009-3419
1999-6187
DOI: 10.3779/j.issn.1009-3419.2023.106.20
Popis: The era of tumor treatment has been revolutionized by the advent of immune checkpoint inhibitors. However, while immunotherapy benefits patients, it can also lead to immune-related adverse events that may affect multiple organs and systems throughout the body, potentially even posing a life-threatening risk. The diverse clinical manifestations and onset times of these adverse events further complicate their prediction and diagnosis. The purpose of this paper is to review the clinical characteristics and predicted biomarkers of adverse events related to inhibitors at immune checkpoints, in order to help clinicians evaluate drug risks and early warn adverse events.
Databáze: Directory of Open Access Journals