Impact of depression on the quality of life of patients with multiple sclerosis

Autor: N. V. Zarubina, N. N. Spirin
Jazyk: ruština
Rok vydání: 2023
Předmět:
Zdroj: Неврология, нейропсихиатрия, психосоматика, Vol 15, Iss 3, Pp 41-47 (2023)
Druh dokumentu: article
ISSN: 2074-2711
2310-1342
DOI: 10.14412/2074-2711-2023-3-41-47
Popis: Multiple sclerosis (MS) is a neurodegenerative disease that leads to multiple focal and diffuse lesions of the central nervous system, resulting in disability of patients. Currently the impact of depression on the quality of life (QoL) of MS patients has been little studied.Objective: to study the effect of depressive disorders on the QoL of patients with MS, to search for factors influencing the development of depression in patients with MS.Material and methods. The study involved 203 MS patients aged 15 to 60 years (mean age 39.7±10.91 years). Disability according to the EDSS scale was 2.51±1.45 points, the average duration of the disease was 8.07±7.22 years. The comparison group consisted of 52 healthy people aged 24 to 43 years (mean age 31.86±6.98 years).Results. Patients with MS in more than half of cases (55.7%) suffer from depressive disorders. In MS patients there was an association of depression with older age, a longer duration of the disease, as well as a higher level of disability and exacerbations (p
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