| Autor: |
James R. Vyvyan, Courtney A. Engles, Scott L. Bray, Erik D. Wold, Christopher L. Porter, Mikhail O. Konev |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2122-2127 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1860-5397 |
| DOI: |
10.3762/bjoc.13.209 |
| Popis: |
Several Hiyama cross-coupling reactions of oxasilacycloalkenes and aryl iodides are described that produce trisubstituted Z-styrenes in moderate to excellent yields. Both electron-rich and electron-poor aryl iodides are tolerated in the cross-coupling reaction. The oxasilacycloalkene coupling partners were prepared by ruthenium-catalyzed intramolecular anti-hydrosilylation of alkynols. One of the cross-coupling products was converted to a 1-benzoxocane, albeit in low yield, using an intramolecular Buchwald–Hartwig etherification. The cyclic ether produced contains the carbon skeleton of heliannuol A. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
