The hypothalamic-pituitary-adrenal axis and the central monoaminergic systems: a pathophysiological link to insomnia with clinical implications

Autor:	Marcio Luciano de Souza Bezerra, Raimundo Nonato Delgado Rodrigues, Ricardo Oliveira Souza
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	autonomic nervous system hypothalamic hormones adrenal cortex hormones sleep sleep deprivation Psychology BF1-990 Consciousness. Cognition BF309-499
Zdroj:	Sleep Science, Vol 15, Iss 01, Pp 128-135 (2022)
Druh dokumentu:	article
ISSN:	1984-0659 1984-0063
DOI:	10.5935/1984-0063.20220032
Popis:	The authors present a theoretical overview of the hypothalamic-pituitary-adrenal axis and the central monoaminergic systems, focusing on a putative pathophysiological relationship to insomnia complaints. Insomnia is an independent and self-perpetuating disorder that requires diagnostic and therapeutic attention in the presence of concomitant disorders, likely with bidirectional influence. An adequate understanding of such mechanisms can help for a better understanding of the interplay between clinical features, neurotransmitters, and the adrenal hypothalamic-pituitary axis may help clinicians to better manage insomnia patients
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/2ffdbb6406b640d79d62add172103abb Zobrazit plný text záznamu View record in DOAJ