| Autor: |
EFSA Panel on Plant Protection Products and their Residues (PPR), Antonio F Hernandez‐Jerez, Paulien Adriaanse, Annette Patrizia Aldrich, Philippe Berny, Sabine Duquesne, Anne Louise Gimsing, Maurice Millet, Olavi Pelkonen, Silvia Pieper, Aaldrik Tiktak, Christopher John Topping, Ioanna Tzoulaki, Anneli Widenfalk, Gerrit Wolterink, Thomas Kuhl, Anja Friel, Frederique Istace, Dimitra Kardassi, Christopher Lythgo, Rositsa Serafimova, Tamara Coja |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
EFSA Journal, Vol 17, Iss 6, Pp n/a-n/a (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1831-4732 |
| DOI: |
10.2903/j.efsa.2019.5712 |
| Popis: |
Abstract The EFSA Panel on Plant Protection Products and their Residues was requested to establish health‐based reference values for groundwater metabolites (LM2, LM3, LM4, LM5 and LM6) of the active substance terbuthylazine based on the available evidence, unless the evidence was considered insufficient to do so. The request was accepted under the explicit circumstance that the reassessment would be made according to a different methodology than the routine methodology currently applied for the assessment of metabolites in groundwater. While for metabolites LM2, LM4 and LM5, it was concluded that the reference values for terbuthylazine are applicable, substance‐specific reference values could not be derived for metabolites LM3 and LM6. The applied threshold of toxicological concern (TTC) approach has shown that metabolites LM3 and LM6 are of potential concern for consumer health, since at least one representative groundwater leaching scenario results in exposure above the relevant threshold. Moreover, other sources of exposure to LM3 and LM6 could not be excluded with certainty. It is therefore recommended to address the specific toxicities of metabolites LM3 and LM6. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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