Does lesion type or severity predict outcome of therapy for horses with equine glandular gastric disease? – A retrospective study

Autor: S. L. Pratt, M. Bowen, G. H. Hallowell, E. Shipman, J. Bailey, A. Redpath
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Veterinary Medicine and Science, Vol 9, Iss 1, Pp 150-157 (2023)
Druh dokumentu: article
ISSN: 2053-1095
54797381
DOI: 10.1002/vms3.1034
Popis: Abstract Background Equine glandular gastric disease (EGGD) is a common condition of the horse. Misoprostol is reported to be superior to oral omeprazole and sucralfate for treatment. Long‐acting intramuscular injectable omeprazole (LAIOMEP) is a novel treatment shown to be effective in a small population. Objectives This study aimed to determine LAIOMEP efficacy compared to misoprostol and oral omeprazole and identify characteristics that predict treatment outcome. Methods All horses that underwent gastroscopy between 2012 and 2019 were reviewed. Lesions were characterised by 4 blinded observers, all of whom are diplomates in equine internal medicine, using established descriptors from the ECEIM consensus statement and subjective severity. Treatment outcome was ranked as worsened, improved or healed. Consensus lesion type, lesion severity and treatment choice were compared to outcome and data screened using univariate analysis (chi‐squared) to determine whether each predicted outcome. Lesion types where univariate analysis predicted a trend (p
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