Autor: |
Meng-Hsuan Hsieh, Kuan-Ta Wu, Yi-Yu Chen, Jeng-Fu Yang, Wen-Yi Lin, Ning-Chia Chang, Chia-Yi Lin, Chao-Kuan Huang, Chao-Ling Wang, Hung-Yi Chuang, Shu-Ching Lin, Yu-Kuei Hsu, Yi-Shan Tsai, Wan-Long Chuang, Ming-Lung Yu, Chia-Yen Dai |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Journal of the Formosan Medical Association, Vol 119, Iss 1, Pp 496-503 (2020) |
Druh dokumentu: |
article |
ISSN: |
0929-6646 |
DOI: |
10.1016/j.jfma.2019.07.007 |
Popis: |
Background/Purpose: Chronic kidney disease (CKD) has become a worldwide health problem, leading to high morbidity and mortality, and non-alcoholic fatty liver disease (NAFLD) is considered a risk factor for CKD. The aim of this study was to explore the relationship between NAFLD fibrosis score (NFS) and the estimated glomerular filtration rate (eGFR), and identify possible risk factors related to the NFS among Taiwanese subjects. Methods: Subjects were enrolled from the database of the Department of Preventive Medicine of Kaohsiung Municipal Hsiao-Kang Hospital. The eGFR was calculated according to the Taiwanese Modification of Diet in Renal Disease (TMDRD) equation, and the NFS was employed to evaluate the fibrotic level. Results: In total, 11,376 subjects were enrolled in this study, with a mean age of 52.0 ± 6.81 years, including 4529 (39.8%) males. A fasting sugar level ≥100 mg/dL (OR = 1.70, 95% CI = 1.52–1.87) and an abnormal waist circumference (OR = 1.81, 95% CI = 1.65–1.99) were significant factors associated with NFS (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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