Quantitative analysis of macular capillaries in diabetic patients using optical coherence tomography angiography

Autor: Lu Nan, Yang Dongni, Gu Yu, Liu Jian, Yang Shilin, Guo Ying, Shan Zhiming, Liu Li, Zhao Wei
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Guoji Yanke Zazhi, Vol 24, Iss 1, Pp 10-17 (2024)
Druh dokumentu: article
ISSN: 1672-5123
DOI: 10.3980/j.issn.1672-5123.2024.1.03
Popis: AIM: To quantify early changes of macular capillary parameters in type 2 diabetic patients using optical coherence tomography angiography(OCTA).METHODS: Retrospective case study. A total of 49 healthy subjects, 52 diabetic patients without retinopathy(noDR)patients, and 43 mild nonproliferative diabetic retinopathy(mNPDR)patients were recruited. Capillary perfusion density, vessel length density(VLD), and average vessel diameter(AVD)were calculated from macular OCTA images(3 mm×3 mm)of the superficial capillary plexus after segmenting large vessels and the deep capillary plexus. Parameters were compared among control subjects, noDR, and mNPDR patients. The area under the receiver operating characteristic curve estimated the abilities of these parameters to detect early changes of retinal microvascular networks.RESULTS: Significant differences were found in the VLD and AVD among the three groups(P
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