Dual-controlled guest release from coordination cages

Autor: Yuqing Yao, Chengyuan Shao, Shuwei Wang, Qiufang Gong, Jia Liu, Hua Jiang, Ying Wang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 2399-3669
DOI: 10.1038/s42004-024-01128-z
Popis: Abstract Despite having significant applications in the construction of controlled delivery systems with high anti-interference capability, to our knowledge dual-controlled molecular release has not yet been achieved based on small molecular/supramolecular entities. Herein, we report a dual-controlled release system based on coordination cages, for which releasing the guest from the cage demands synchronously altering the coordinative metal cations and the solvent. The cages, Hg 5 L 2 and Ag 5 L 2 , are constructed via coordination-driven self-assembly of a corannulene-based ligand. While Hg 5 L 2 shows a solvent-independent guest encapsulation in all the studied solvents, Ag 5 L 2 is able to encapsulate the guests in only some of the solvents, such as acetone-d6, but will liberate the encapsulated guests in 1,1,2,2-tetrachloroethane-d2. Hg 5 L 2 and Ag 5 L 2 are interconvertible. Thus, the release of guests from Hg 5 L 2 in acetone-d6 can be achieved, but requires two separate operations, including metal substitutions and a change of the solvent. Dual-controlled systems as such could be useful in complicated molecular release process to avoid those undesired stimulus-responses.
Databáze: Directory of Open Access Journals
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