Haemolymph of Cold-Adapted Baikal Endemic Amphipods as a Promising Source for Screening of Novel Natural Products

Autor: Axenov-Gribanov D.V., Protasov E.S., Voytsekhovskaya I.V., Shatilina Z.M., Rzhechitskiy Y.A., Dimova M.D., Kostka D.V., Lubyaga Y.A., Timofeyev M.A.
Jazyk: English<br />Russian
Rok vydání: 2017
Předmět:
Zdroj: Journal of Stress Physiology & Biochemistry, Vol 13, Iss 4, Pp 74-80 (2017)
Druh dokumentu: article
ISSN: 1997-0838
Popis: The aim of this study was to assess the possibility to use Baikal endemic amphipods as a source for screening of novel natural products. Analysis of amphipod’s E. verrucosus hemolymph by HPLC-MS was performed for the first time. A number of natural products with new molecular mass for Baikal endemic macroinvertebrates were found. We found a compound as chrysin by comparison of MS1, MS2 profiles and molecular mass of natural products registered in Dictionary of Natural Products and MZ-cloud databases. Also, we found new compound with mass 493.80277 Da, circulating in the amphipod’s hemolymph.
Databáze: Directory of Open Access Journals