Difference in vaginal microecology, local immunity and HPV infection among childbearing-age women with different degrees of cervical lesions in Inner Mongolia

Autor: Jing-Jing Zheng, Jing-Hui Song, Cong-Xiang Yu, Fei Wang, Peng-Cheng Wang, Jing-Wei Meng
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Women's Health, Vol 19, Iss 1, Pp 1-8 (2019)
Druh dokumentu: article
ISSN: 1472-6874
DOI: 10.1186/s12905-019-0806-2
Popis: Abstract Background This study aims to investigate the difference in vaginal microecology, local immunity and HPV infection among childbearing-age women with different degrees of cervical lesions. Methods A total of 432 patients were included in this study. Among these patients, 136 patients had LSIL, 263 patients had HSIL and 33 patients had CSCC. These patients were assigned as the research groups. In addition, 100 healthy females were enrolled and assigned as the control group. Results The microbiological indexes of vaginal secretions were evaluated. Furthermore, the concentrations of SIgA, IgG, IL-2 and IL-10 in vaginal lavage fluid, as well as the presence of HPV, mycoplasma and Chlamydia in cervical secretions, were detected. The results is that: (1) Differences in evaluation indexes of vaginal microecology among all research groups and the control group were statistically significant (P
Databáze: Directory of Open Access Journals
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