Autor: |
Erin D Michos, Joshua J Joseph, Ian H de Boer, Alain G Bertoni, Justin Basile Echouffo-Tcheugui, Sherita H Golden, Guy Brock, Songzhu Zhao, David Kline, Amaris Williams, Valery S Effoe, Bryan Kestenbaum |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
BMJ Open Diabetes Research & Care, Vol 10, Iss 5 (2022) |
Druh dokumentu: |
article |
ISSN: |
2052-4897 |
DOI: |
10.1136/bmjdrc-2022-002931 |
Popis: |
Introduction Higher concentrations of serum 25-hydroxyvitamin D (25(OH)D) and lower concentrations of parathyroid hormone (PTH) are associated with lower insulin resistance and incident diabetes in non-Hispanic White and Hispanic Americans. Results are mixed in other populations, with no observational studies in a large multiethnic cohort. The association of serum 25(OH)D with diabetes may vary by adiposity level.Research design and methods Among 5611 participants in the Multi-Ethnic Study of Atherosclerosis without diabetes at baseline, cross-sectional associations of serum 25(OH)D with homeostasis model assessment of insulin resistance (HOMA-IR) and HOMA-β were examined using linear regressions. The association of 25(OH)D with incident diabetes over 9 years was examined using Cox proportional hazard regression.Results Black Americans had the highest proportion of individuals with 25(OH)D |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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