Coexistence of restless legs syndrome and multiple sclerosis aggravates anxiety and depression

Autor: Serhan SEVIM, Meltem DEMIRKIRAN, Murat TERZI, Nur YÜCEYAR, Bahar TAŞDELEN, Egemen İDIMAN, Murat KÜRTÜNCÜ, Cavit BOZ, Deniz TUNCEL, Rana KARABUDAK, Aksel SIVA, Abdülcemal ÖZCAN, Münife NEYAL, Başak Karakurum GÖKSEL, Gülcan Baran GAZALOĞLU, Mehmet BALAL, Sedat ŞEN, Meltem Alkaya BAKLAN, Tuncay GÜNDÜZ, Aslı TUNCER, Uğur UYGUNOĞLU
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Arquivos de Neuro-Psiquiatria (2022)
Druh dokumentu: article
ISSN: 1678-4227
0004-282x
DOI: 10.1590/0004-282x-anp-2020-0400
Popis: ABSTRACT Background: Among the comorbidities that accompany multiple sclerosis (MS), restless legs syndrome (RLS) is one of the most common. Anxiety and depression are common psychological comorbidities that impact the quality of life of patients with MS (PwMS), as well as patients with RLS. Objective: To investigate the psychiatric burden of MS and RLS coexistence, we conducted a nationwide, multicenter and cross-sectional survey. Methods: Participants were assessed by using demographic and clinical parameters along with the Hamilton Anxiety and Hamilton Depression Scales (HAM-A and HAM-D). Results: Out of the 1,068 participants, 173 (16.2%) were found to have RLS [RLS(+)] and 895 (83.8%) did not [RLS(-)]. The mean scores for HAM-A and HAM-D were significantly higher among RLS(+) subjects than among RLS(-) subjects (p
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