Beyond Traditional Structure-Based Drug Design: The Role of Iron Complexation, Strain, and Water in the Binding of Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylase 2

Autor: Scott D. Bembenek, Hariharan Venkatesan, Hillary M. Peltier, Mark D. Rosen, Terrance D. Barrett, Kimon C. Kanelakis, Heather L. Palomino, Theresa I. Brondstetter, Taraneh Mirzadegan, Michael H. Rabinowitz
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: ACS Omega, Vol 4, Iss 4, Pp 6703-6708 (2019)
Druh dokumentu: article
ISSN: 2470-1343
DOI: 10.1021/acsomega.9b00199
Databáze: Directory of Open Access Journals