Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans

Autor: Jae-Hyung Jin, Kyung-Tae Lee, Joohyeon Hong, Dongpil Lee, Eun-Ha Jang, Jin-Young Kim, Yeonseon Lee, Seung-Heon Lee, Yee-Seul So, Kwang-Woo Jung, Dong-Gi Lee, Eunji Jeong, Minjae Lee, Yu-Byeong Jang, Yeseul Choi, Myung Ha Lee, Ji-Seok Kim, Seong-Ryong Yu, Jin-Tae Choi, Jae-Won La, Haneul Choi, Sun-Woo Kim, Kyung Jin Seo, Yelin Lee, Eun Jung Thak, Jaeyoung Choi, Anna F. Averette, Yong-Hwan Lee, Joseph Heitman, Hyun Ah Kang, Eunji Cheong, Yong-Sun Bahn
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18028-0
Popis: Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.
Databáze: Directory of Open Access Journals