| Autor: |
Sedigheh Esmaeilzadeh, Eisa Tahmasbpour, Maryam Gholinezhad-Chari |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Middle East Fertility Society Journal, Vol 22, Iss 2, Pp 149-155 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1110-5690 |
| DOI: |
10.1016/j.mefs.2017.01.007 |
| Popis: |
Objectives: Polycystic ovary syndrome (PCOS) is a common disease among young women that causes hyperinsulinemia. Hyperhomocysteinemia is shown to be correlated positively with the hyperinsulinemia. This study aimed to evaluate serum homocysteine (Hcy) level and its correlation with other serum metabolic amongst over weight, obese and non-obese PCOS women. Methods: Sixty women with PCOS and 20 healthy subjects were studied. Hormonal assays, lipid profile, Hcy and fasting insulin levels, insulin resistance (IR) indices (HOMA and QUICKI) determinations and ultrasound evaluation were performed. Results: Mean of BMI was significantly higher in PCOS subjects as compared with the controls (29.95 ± 4.91 vs 26.09 ± 4.80 kg/m2; p = 0.005). The mean fasting insulin levels were also significantly higher (17.80 ± 8.02 vs 11.55 ± 6.81 μU/dl; p = 0.003) where we found no difference in fasting glucose concentrations between groups. IR indices in PCOS women were significantly higher than control group (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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