Mycobacterium tuberculosis infection in a HIV-positive patient

Autor: Maria Theresa Montales, Alexandria Beebe, Arun Chaudhury, Naveen Patil
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 16, Iss C, Pp 160-162 (2015)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2015.10.006
Popis: Mycobacterium tuberculosis (MTB) and human immunodeficiency virus (HIV) coinfection remains a global public health challenge. We report a 40 year old African American male who is a known HIV-positive patient, non-compliant with his antiretrovirals and developed pulmonary tuberculosis. His chief complaints were chronic cough, fever, night sweats and undocumented weight loss. He had a prior positive T-SPOT-TB test; however, chest radiograph and sputum smear examination revealed normal results. PCR-based GeneXPERT MTB/RIF assay was ordered and confirmed MTB infection. The sputum cultures grew MTB and sensitivities showed susceptibility to all primary anti-tuberculosis medications. A delay in diagnosis and initiation of MTB therapy, in the setting of HIV or AIDS, may result in rapid disease progression and worse clinical outcome.
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