| Autor: |
Mojgan Alaeddini, Shahroo Etemad-Moghadam |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Brazilian Journal of Otorhinolaryngology, Vol 88, Iss 4, Pp 529-532 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1808-8694 |
| DOI: |
10.1016/j.bjorl.2020.07.010 |
| Popis: |
Introduction: Proliferation markers play a significant role in the biologic behavior of tumors. Geminin is a known inhibitor of the cell cycle and DNA replication and has not been previously reported in cutaneous basal and squamous cell carcinomas of the head and neck. Objectives: We aimed to investigate proliferation markers ki67, MCM2, and geminin in head and neck cutaneous basal and squamous cell carcinomas. Methods: Forty cases of each tumor were immuostained with ki67, MCM2, and geminin followed by assessment of labeling indices (LIs). MCM2/ki67- and geminin/ki67-ratios were also determined; t-test was used for statistical analysis (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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