An unusual presentation of Castleman's Disease:a case report

Autor: Izuchukwu Ifeoma S, Tourbaf Kamal, Mahoney Martin C
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Zdroj: BMC Infectious Diseases, Vol 3, Iss 1, p 20 (2003)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/1471-2334-3-20
Popis: Abstract Background Castleman's disease (CD), a rare condition of uncertain etiology, involves a massive proliferation of lymphoid tissues and typically presents as mediastinal masses. We describe a patient with CD who presented with diffuse adenopathy involving the inguinal, paratracheal, retroperitoneal, axillary, and pelvic regions. Case presentation Case report describing presentation, work-up, management and clinical course of a patient with Castleman's disease in the setting of a county hospital in metropolitan area. Patient was treated with chemotherapeutic agents. Conclusions To our knowledge, this represents the first case of CD involving an HIV-positive patient with a negative Human Herpes Virus (HHV-8) viral panel. Because patients with similar clinical histories are at high risk for the development of non-Hodgkin's lymphoma and Kaposi sarcoma, regular medical surveillance is recommended.
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