| Autor: |
Arrigo F.G. Cicero, Federica Fogacci, Martina Rosticci, Angelo Parini, Marina Giovannini, Maddalena Veronesi, Sergio D’Addato, Claudio Borghi |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Nutrition & Metabolism, Vol 14, Iss 1, Pp 1-7 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1743-7075 |
| DOI: |
10.1186/s12986-017-0214-2 |
| Popis: |
Abstract Background Phytosterols and red yeast rice are largely studied cholesterol-lowering nutraceuticals, respectively inhibiting the bowel absorption and liver synthesis of cholesterol. Our aim was to test the effect on lipid profile of phytosterols, red yeast rice and their association. Methods We performed a three parallel arms, double blind, clinical trial randomizing 90 moderately hypercholesterolemic subjects to treatment with phytosterols 800 mg (group 1), red yeast rice standardized to contain 5 mg monacolins from Monascus purpureus (group 2), or both combined nutraceuticals (group 3). Results After 8 weeks of treatment, in group 1 no significant variation of lipid parameters has been detected. In group 2 a significant reduction (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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