Predictors of cardiovascular events in patients with heart failure and Pseudomonas aeruginosa pneumonia

Autor: V. I. Podzolkov, A. I. Tarzimanova, L. A. Ponomareva, E. E. Sokolova, A. A. Chinova, E. N. Popova, A. B. Ponomarev, I. Zh. Loria, T. S. Vargina, Zh. M. Sizova, N. K. Ziskina
Jazyk: ruština
Rok vydání: 2024
Předmět:
Zdroj: Российский кардиологический журнал, Vol 29, Iss 4 (2024)
Druh dokumentu: article
ISSN: 1560-4071
2618-7620
DOI: 10.15829/1560-4071-2024-5817
Popis: Aim. To identify predictors of cardiovascular events (CVEs) in patients with heart failure (HF) and P. aeruginosa pneumonia.Material and methods. The study included 92 patients with HF with mildly reduced or reduced ejection fraction and nosocomial pneumonia. Based on sputum or bronchoalveolar lavage microbiological examination, patients were divided into 2 following groups: group I — 51 patients with HF and P. aeruginosa pneumonia, group II — 41 patients with HF and pneumonia caused by other pathogens (Staphylococcus aureus, Streptococcus pneumoniae). During the hospital stay, the following morbidities were assessed: cardiovascular death, acute coronary syndrome, non-fatal cerebrovascular accident, pulmonary embolism, lower extremity venous thrombosis.Results. CVEs were significantly more often observed in patients with HF and P. aeruginosa pneumonia — 30 (58,8%) than in patients with HF and pneumonia caused by S. aureus or S. pneumoniae — 5 (12,1%). Complete blood count in group I patients revealed a decrease in hemoglobin level to 114 [95; 133] g/l, when compared with patients in group II — 139 [118; 150] g/l (p11×109/l (RR 2,412; 95% CI 1,399-4,158; p=0,048), CRP >133 mg/l (RR 3,115; 95% CI 1,611-6,025; p
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