State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
| Autor: | V. P. Mikhin, U. A. Boldyreva, M. A. Chernyatina, N. I. Gromnatsky |
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| Jazyk: | ruština |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Архивъ внутренней медицины, Vol 0, Iss 5, Pp 40-44 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2226-6704 2411-6564 |
| DOI: | 10.20514/2226-6704-2015-0-5-15 |
| Popis: | A randomized study of the state of stiffness parameters arteries wall (CAVI — cardio-ankle vascular index), AI (augmentation index) PEP (duration of the voltage of the left ventricle) using «VaSera-1000» («Fukuda Denshi», Japan) in primary hypertension patients (80) not treated with systemic antihypertensive therapy. The effect of long-term (3 months) was be marketed. Losartan combined with Mexicor 300mg/day or mildronate 1000 mg/day for the specified parameters. It sets the initial reduction the properties of the arterial wall in patients with hypertension, in contrast to healthy individuals. Mexicor or mildronat accompanied by improvement east-cal properties of the arterial wall, reducing CAVI and AI in 3 months on 9.4% and 8.9%, 14.9% and 15.4%, respectively. In the control group-term change CAVI and AI no. Mexicor led to a more pronounced increase in PEP, than mildronate, respectively, on 23.7% and 18.9%. Losartan monotherapy results in a less pronounced decrease in the stiffness of the vessel wall. |
| Databáze: | Directory of Open Access Journals |
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