Comparative analysis of addiction severity and renal functions in patients with synthetic cannabinoid use disorder versus cannabis use disorder

Autor: Rana Walid Hamimy, Momtaz Mohamed Abd El Wahab, Rania Mamdouh Mohamed
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Middle East Current Psychiatry, Vol 31, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 2090-5416
DOI: 10.1186/s43045-024-00442-5
Popis: Abstract Background The use of synthetic cannabinoids (SC) has become a concerning public health issue due to their potential adverse effects on both physical and mental health. Understanding the effect of cannabis and synthetic cannabinoids use on kidney functions and creatinine phosphokinase-total (CPK) levels is essential for targeted intervention and patient care. Methods This cross-sectional study aimed to assess addiction severity using the Addiction Severity Index (ASI) and kidney functions in 45 patients with SC use disorder and compare them to 45 patients with cannabis use disorder (CUD). Participants were recruited from the addiction outpatient clinics and inpatient ward of the addiction psychiatry unit at “Kasr Al Aini Hospital,” Cairo University. Results There was a statistically significant difference between the 2 groups regarding the Addiction Severity Index domains, where patients with SC use disorder had higher scores in all domains of the ASI. Regarding kidney functions and CPK-total levels, there was a significant difference in the serum CPK-total level (p
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